Mastering 'Metrics: The Path from Cause to Effect, by Joshua Angrist and Jörn-Steffen Pischke, is to be published by Princeton University Press later this month. This new book from the authors of Mostly Harmless Econometrics: An Empiricist's Companion is bound to be well received by students and researchers involved in applied empirical economics. My guess is that the biggest accolades will come from those whose interest is in empirical microeconomics.
You can download and preview the Introduction and Chapter 1.
Apparently the book focuses on:
"The five most valuable econometric methods, or what the authors call the Furious Five - random assignment, regression, instrumental variables, regression discontinuity designs, and differences in differences."
If this sounds interesting to you, then make sure that you take a look at Peter Dizikes' recent post, "How to Conduct Social Science Research", on the World Economic Forum website.